QUALITATIVE AND QUANTITATIVE COMPOSITION

Kalma tablets contain alprazolam, an anti-anxiety, benzodiazepine derivative chemically and
pharmacologically related to other drugs of this class. Buy Mylan Kalma 2mg for sale online Australia
Each Kalma 0.25 tablet contains 0.25 mg of alprazolam; each Kalma 0.5 tablet contains 0.5 mg of alprazolam;
each Kalma 1 tablet contains 1 mg of alprazolam; each Kalma 2 tablet contains 2 mg of alprazolam.
Kalma also contains sugars (as lactose), benzoates and sulfites.
For the full list of excipients, see Section 6.1 LIST OF EXCIPIENTS.

 PHARMACEUTICAL FORM

Kalma 0.25: alprazolam 0.25 mg tablet: white, oval, marked AL0.25 on one side, G on reverse.
Kalma 0.5: alprazolam 0.5 mg tablet: pale pink, oval, marked AL0.5 on one side, G on reverse.
Kalma 1: alprazolam 1 mg tablet: pale blue, oval, marked AL1.0 on one side, G on reverse.
Kalma 2: alprazolam 2 mg tablet: approximately 9.5 mm x 9.0 mm, white, oval, bevel edged, quadrisect tablet
marked “A” in the upper left quadrant, “L” in the upper right quadrant, “G” in the lower left quadrant and “2”
in the lower right quadrant on one side, and plain quadrisect on the other side.

 CLINICAL PARTICULARS

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Anxiety
Short-term symptomatic treatment of anxiety including treatment of anxious patients with some symptoms of
depression.
Panic disorder
The treatment of panic disorder with or without some phobic avoidance, and for blocking or attenuation of
panic attacks and phobias in patients who have agoraphobia with panic attacks.
The diagnostic criteria for panic disorder in DSM-III-R are as follows:
The panic attacks (discrete periods of intense fear or discomfort), at least initially, are unexpected. Later in the
course of this disturbance, certain situations (e.g. driving a car or being in a crowded place) may become
associated with having a panic attack. These panic attacks are not triggered by situations in which the person
is the focus of others’ attention (as in social phobia). Buy Mylan Kalma 2mg for sale online Australia

SPECIAL WARNINGS AND PRECAUTIONS FOR USE

Identified Precautions
Depression, Psychosis and Schizophrenia
Alprazolam is not recommended as primary therapy in patients with depression and psychosis. In such
conditions, psychiatric assessment and supervision are necessary if benzodiazepines are indicated.
Benzodiazepines may increase depression in some patients, and may contribute to deterioration in severely
disturbed schizophrenics with confusion and withdrawal. Suicidal tendencies may be present or uncovered
and protective measures may be required.
Panic related disorders have been associated with depression and an increased frequency of suicide amongst
untreated patients has been reported. Therefore, the precautions exercised when using any psychotropic drug
in depressed patients or potentially suicidal patients should be applied when using higher doses of alprazolam
in patients with panic related disorders Episodes of hypomania and mania have been reported in association
with the use of alprazolam in patients with depression. Buy Mylan Kalma 2mg for sale online Australia